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| Cápua,Maria Luísa Buffo de; Coleta,Flávia Eiras Dela; Miotto,Mariana Rodrigues; Calazans,Sabryna Gouveia; Godoy,Aline Vieira; Nakage,Ana Paula Massae; Lisbão,Carolina Bonduki Sales; Daleck,Carlos Roberto; Santana,Aureo Evangelista. |
| The objective of this study is to provide the first report of bone marrow transplantation (BMT) in dogs in Brazil. A Rottweiler with cutaneous lymphoma was submitted to a twelve-week Madison-Wisconsin chemotherapy protocol followed by autologous bone marrow transplantation. For this, 10mL kg-1 of bone marrow was collected simultaneously from both iliac crests and cryopreserved in a freezer at -80°C. The conditioning step was performed by administering cyclophosphamide by intravenous route at 400mg m-2. Bone marrow was reinfused after defrosting in a water bath at 37°C. Bone marrow nucleated cell counts before and after freezing, showed a small relative loss of nucleated cells (35.10 and 31.80x10³µL-1 , respectively). Cyclophosphamide induced neutropenia... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Canine; Cutaneous lymphoma; Autologous bone marrow transplant; Chemotherapy. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782009000200045 |
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